If the iOS device is in single app mode but online it would honor the device wipe. If it was offline the thief would still be able to erase the device using Recovery Mode and then they would be unable to enroll so it is still bricked to them.
If the iOS device is in single app mode but online it would honor the device wipe. If it was offline the thief would still be able to erase the device using Recovery Mode and then they would be unable to enroll so it is still bricked to them.